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欧盟评估转基因酿酒酵母菌株CBS 615.94生产的α-半乳糖苷酶的安全性

时间: 2024-03-08 来源: 食品伙伴网
核心提示:
2024年3月4日,欧盟食品安全局就一种α-半乳糖苷酶(α-galactosidase)的安全性评价发布意见。
   食品伙伴网讯  2024年3月4日,欧盟食品安全局就一种α-半乳糖苷酶(α-galactosidase)的安全性评价发布意见。
 
  据了解,这种食品酶是由转基因酿酒酵母菌株CBS 615.94生产的,旨在用于瓜尔豆胶的加工中。
 
  经过评估,专家小组认为,在预期的使用条件下,不能排除饮食暴露引起过敏反应的风险,但这种情况发生的可能性很低。根据所提供的数据,评估小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme α-galactosidase (α-d-galactoside galactohydrolase; EC 3.2.1.22) is produced with the genetically modified Saccharomyces cerevisiae strain CBS 615.94 by Kerry Ingredients & Flavours Ltd. The production strain of the food enzyme contains multiple copies of a known antimicrobial resistance gene. However, based on the absence of viable cells and DNA from the production organism in the food enzyme, this is not considered to be a risk. As no other concerns arising from the genetically modified microbial source or from the manufacturing process have been identified, the Panel considered that toxicological tests were not needed for the assessment of this food enzyme. The food enzyme is intended to be used in guar gum processing. The dietary exposure was estimated to be up to 0.828 mg TOS/kg body weight per day in European populations. A search for the similarity of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel considered that a risk of allergic reactions by dietary exposure cannot be excluded, but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
 
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